国产热热热精品,亚洲视频久久】日韩,三级婷婷在线久久,99人妻精品视频,精品九热人人肉肉在线,AV东京热一区二区,91po在线视频观看,久久激情宗合,青青草黄色手机视频

USEUROPEAFRICAASIA 中文雙語Fran?ais
World
Home / World / Africa

Chinese herb compound shows promise as treatment for Ebola: study

Xinhua | Updated: 2015-02-27 10:55

WASHINGTON - Tetrandrine, a compound common in Chinese traditional medicine, has been found effective in treating the deadly Ebola virus disease in mice, US and German researchers said Thursday.

This may be due to the drug's ability to block two channels needed by the virus to move within a cell and infect it completely, they reported in the US journal Science.

"We are very excited about the progress made in this study and the momentum it provides as scientists across the world vigorously search for effective vaccines and treatments against Ebola virus," lead author Robert Davey of Texas Biomedical Research Institute said in a statement.

Ebola virus begins its entry into a cell by first binding to several types of cell surface proteins. Then the virus is taken into the cell and follows an endosomal route, or membrane-bound route that transports the virus to various cell compartments to complete infection.

The new study identified two calcium channels in endosomes, called two pore channels (TPCs), that control the movement of the Ebola virus within the cells and found that these channels can be blocked therapeutically with several drugs currently used to treat high blood pressure.

Working with a group in Munich, Germany and Southwest Research Institute, Davey's team found Tetrandrine was the most potent blocker of TPCs in mice.

"Starting Tetrandrine treatment soon after infection significantly enhanced the survival of mice without any detectable side effects ... when the treatment was started one day after virus challenge, half the mice survived," their paper wrote. " These results indicate that Tetrandrine is highly effective against disease in mice."

An accompanying article published by Science warned the findings don't indicate that "a viable treatment is close at hand. "

Tetrandrine has not been tested in a macaque model, the "gold standard" for Ebola drug efficacy testing, and it's not approved for use in humans except in China, the article said, noting that the dose given to mice may be toxic when its equivalent is used in humans.

"Given the mode of action, it seems unlikely that Tetrandrine treatment would be superior to the most advanced Ebola post-exposure treatments," it wrote.

So far, there have been more than 9,400 deaths since the Ebola outbreak began last year in Liberia, Sierra Leone and Guinea. The virus causes hemorrhagic fever in humans and currently has no approved therapy or vaccine.

Most Viewed in 24 Hours
Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
万州区| 绥棱县| 疏勒县| 泾源县| 定安县| 莆田市| 宁河县| 昂仁县| 涡阳县| 汉中市| 芦溪县| 游戏| 邓州市| 盐山县| 东方市| 河东区| 诸城市| 中卫市| 北票市| 孟州市| 江孜县| 大港区| 北安市| 孟州市| 灌阳县| 玉龙| 康平县| 文昌市| 安多县| 台东市| 巴林左旗| 寿光市| 赤壁市| 道孚县| 武功县| 康乐县| 碌曲县| 酉阳| 库尔勒市| 隆化县| 凉山|