国产热热热精品,亚洲视频久久】日韩,三级婷婷在线久久,99人妻精品视频,精品九热人人肉肉在线,AV东京热一区二区,91po在线视频观看,久久激情宗合,青青草黄色手机视频

Global EditionASIA 中文雙語(yǔ)Fran?ais
China
Home / China / Health

Chinese scientists reveal potential driver of ulcerative colitis

Xinhua | Updated: 2025-11-24 16:56
Share
Share - WeChat

NANJING -- A research team from Nanjing University has discovered a novel gut bacterium that acts as a potential driver of ulcerative colitis, paving the way for new treatment approaches. The findings were published on Friday in the journal Science.

Ulcerative colitis is characterized by chronic abdominal pain, diarrhea, and bloody, purulent stools. According to Zhu Minsheng, a professor at the university, current treatments only relieve inflammatory symptoms rather than providing a cure, due to unclear pathogenic mechanisms. Some severe cases require colectomy, which carries significant side effects and high recurrence rates.

The team discovered aerolysin in fecal bacterial cultures from ulcerative colitis patients and isolated the pathogen responsible for its production. Whole-genome sequencing and physiological-biochemical tests identified these strains as a novel Aeromonas subspecies, named MTB.

In a cohort of 79 Chinese patients, over 70 percent tested positive for MTB in their stool samples. "Unlike other Aeromonas species, MTB has a strong intestinal colonization ability," said Jiang Zhihui, first author of the study.

"Antibiotic overuse or intestinal damage can promote MTB colonization, and its persistent presence in the gut contributes to the high recurrence rate of ulcerative colitis," Jiang added.

Zhu revealed that the team has prepared anti-aerolysin neutralizing antibodies, which have produced promising results in mouse models.

Top
BACK TO THE TOP
English
Copyright 1994 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
 
镇远县| 巴南区| 广州市| 宜都市| 建湖县| 会泽县| 淮北市| 平凉市| 郑州市| 五峰| 黄梅县| 房山区| 江门市| 五原县| 西林县| 巩留县| 桃源县| 读书| 连江县| 苍溪县| 吐鲁番市| 广饶县| 马尔康县| 新巴尔虎左旗| 江西省| 淳化县| 灵丘县| 舟山市| 宝丰县| 琼海市| 兴义市| 仁布县| 台湾省| 平谷区| 河北区| 沧州市| 锡林浩特市| 陆河县| 南丹县| 茶陵县| 冷水江市|